|Other Names||Geminin coiled-coil domain-containing protein 1, GMNC, GEMC1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2- dependent recruitment of CDC45L onto replication origins (By similarity).|
|Cellular Location||Nucleus. Note=Associates with chromatin during pre-replication complex (pre-RC) formation|
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GEMC1is a regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1-and CDK2-dependent recruitment of CDC45L onto replication origins (By similarity).
Muzny, D.M., et al. Nature 440(7088):1194-1198(2006)
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