|Other Names||ADP/ATP translocase 3, ADP, ATP carrier protein 3, ADP, ATP carrier protein, isoform T2, ANT 2, Adenine nucleotide translocator 3, ANT 3, Solute carrier family 25 member 6, ADP/ATP translocase 3, N-terminally processed, SLC25A6, ANT3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the mitochondrial carriersubfamily of solute carrier protein genes. The product of this genefunctions as a gated pore that translocates ADP from themitochondrial matrix into the cytoplasm. The protein is implicatedin the function of the permability transition pore complex (PTPC),which regulates the release of mitochondrial products that induceapoptosis. The human genome contains several non-transcribedpseudogenes of this gene.
Danishuddin, M., et al. J Mol Model 16(3):535-541(2010)Hu, Z., et al. FEBS Lett. 583(2):383-388(2009)Yang, Z., et al. Mol. Biol. Cell 18(11):4681-4689(2007)Tu, L.C., et al. Mol. Cell Proteomics 6(4):575-588(2007)Jang, J.Y., et al. Cell. Immunol. 241(1):14-25(2006)
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