|Other Names||Sialidase-2, Cytosolic sialidase, N-acetyl-alpha-neuraminidase 2, NEU2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moities from glycoproteins, oligosaccharides and gangliosides.|
|Tissue Location||Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2-D1|
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This gene belongs to a family of glycohydrolytic enzymeswhich remove sialic acid residues from glycoproteins andglycolipids. Expression studies in COS7 cells confirmed that thisgene encodes a functional sialidase. Its cytosolic localization wasdemonstrated by cell fractionation experiments. [provided byRefSeq].
Stoppani, E., et al. Cell Biol. Int. 33(9):1020-1025(2009)Li, C.Y., et al. Cell Res. 17(4):357-362(2007)Chavas, L.M., et al. J. Biol. Chem. 280(1):469-475(2005)Seyrantepe, V., et al. J. Biol. Chem. 279(35):37021-37029(2004)Tringali, C., et al. J. Biol. Chem. 279(5):3169-3179(2004)
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