|Other Names||Cytosolic purine 5'-nucleotidase, Cytosolic 5'-nucleotidase II, NT5C2, NT5B, NT5CP, PNT5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||NT5B, NT5CP, PNT5|
|Function||May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.|
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Provided below are standard protocols that you may find useful for product applications.
Purine 5-prime-nucleotidase (EC 184.108.40.206) preferentiallyhydrolyzes inosine 5-prime-monophosphate (IMP) and other purinenucleotides, and is allosterically activated by various compounds,including ATP. The enzyme is exclusively located in the cytoplasmicmatrix of cells and may have a critical role in the maintenance ofa constant composition of intracellular purine/pyrimidinenucleotides in cooperation with other nucleotidases.[supplied byOMIM].
Niu, W., et al. Clin. Chim. Acta 411 (19-20), 1491-1495 (2010) :Yamauchi, T., et al. Biochem. Pharmacol. 77(12):1780-1786(2009)Newton-Cheh, C., et al. Nat. Genet. (2009) In press :Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Jordheim, L.P., et al. Drug Metab. Dispos. 36(12):2419-2423(2008)
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