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SNIP1 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8TAD8
Clone Names 101109038
Additional Information
Gene ID 79753
Other Names Smad nuclear-interacting protein 1, FHA domain-containing protein SNIP1, SNIP1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNIP1
Function Required for pre-mRNA splicing as component of the spliceosome (PubMed:29360106). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
Cellular Location Nucleus
Tissue Location Ubiquitous, with highest expression in heart and skeletal muscle.
Research Areas
Citations (0)
citation

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Background

Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. SNIP1 is involved in the microRNA (miRNA) biogenesis.

References

Bracken, C.P., et al. Cancer Res. 68(18):7621-7628(2008)Yu, B., et al. Proc. Natl. Acad. Sci. U.S.A. 105(29):10073-10078(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 277.78
Cat# BP12249a
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