SNIP1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8TAD8 |
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Clone Names | 101109038 |
Gene ID | 79753 |
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Other Names | Smad nuclear-interacting protein 1, FHA domain-containing protein SNIP1, SNIP1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SNIP1 |
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Function | Required for pre-mRNA splicing as component of the spliceosome (PubMed:29360106). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. |
Cellular Location | Nucleus |
Tissue Location | Ubiquitous, with highest expression in heart and skeletal muscle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. SNIP1 is involved in the microRNA (miRNA) biogenesis.
References
Bracken, C.P., et al. Cancer Res. 68(18):7621-7628(2008)Yu, B., et al. Proc. Natl. Acad. Sci. U.S.A. 105(29):10073-10078(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)
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