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DCDC1 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P59894
Clone Names 100309233
Peptide ID 100309233
Additional Information
Other Names Doublecortin domain-containing protein 1, DCDC1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCDC1
Tissue Location Highly expressed in testis. Lower levels of expression in lung, kidney, and pancreas. Higher expression in fetal brain than in adult brain. EMBL; AY247970; AAP75563.1; -; mRNA EMBL; AK126066; BAC86423.2; -; mRNA EMBL; AL133296; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL133349; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL133376; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL135932; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL137160; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL162614; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL137804; -; NOT_ANNOTATED_CDS; Genomic_DNA CCDS; CCDS7872.1; -. [P59894-1] RefSeq; NP_861523.2; NM_181807.3. [P59894-1] UniGene; Hs.127405; - UniGene; Hs.530438; - UniGene; Hs.592000; - UniGene; Hs.729691; - UniGene; Hs.730375; - ProteinModelPortal; P59894; - BioGrid; 131112; 1 STRING; 9606.ENSP00000389792; - iPTMnet; P59894; - PhosphoSitePlus; P59894; - BioMuta; DCDC1; - DMDM; 160332323; - PaxDb; P59894; - PeptideAtlas; P59894; - PRIDE; P59894; - ProteomicsDB; 57166; - DNASU; 341019; - Ensembl; ENST00000342355; ENSP00000343496; ENSG00000170959. [P59894-2] Ensembl; ENST00000452803; ENSP00000389792; ENSG00000170959. [P59894-1] GeneID; 341019; - KEGG; hsa:341019; - UCSC; uc001msu.3; human. [P59894-1] CTD; 341019; - EuPathDB; HostDB:ENSG00000170959.14; - GeneCards; DCDC1; - H-InvDB; HIX0009525; - HGNC; HGNC:20625; DCDC1 MIM; 608062; gene neXtProt; NX_P59894; - OpenTargets; ENSG00000170959; - PharmGKB; PA134970075; - eggNOG; ENOG410KDIP; Eukaryota eggNOG; ENOG41122B9; LUCA GeneTree; ENSGT00390000012809; - HOGENOM; HOG000112174; - HOVERGEN; HBG051318; - InParanoid; P59894; - PhylomeDB; P59894; - TreeFam; TF329467; - ChiTaRS; DCDC1; human GenomeRNAi; 341019; - PRO; PR:P59894; - Proteomes; UP000005640; Chromosome 11 Bgee; ENSG00000170959; - CleanEx; HS_DCDC1; - ExpressionAtlas; P59894; baseline and differential GO; GO:0005622; C:intracellular; IEA:GOC GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro Gene3D; 3.10.20.230; -; 1 InterPro; IPR003533; Doublecortin_dom InterPro; IPR036572; Doublecortin_dom_sf SUPFAM; SSF89837; SSF89837; 2 PROSITE; PS50309; DC; 1 2: Evidence at transcript level; Alternative splicing; Complete proteome; Polymorphism; Reference proteome CHAIN 1 354 Doublecortin domain-containing protein 1 /FTId=PRO_0000079803 DOMAIN 168 252 Doublecortin. {ECO:0000255|PROSITE- ProRule:PRU00072} VAR_SEQ 252 270 DHLLLIKKVTWTMNGLMLP -> GFRYLYNKNESKFTSQIF L (in isoform 2) /FTId=VSP_056951 VAR_SEQ 271 354 Missing (in isoform 2) /FTId=VSP_056952 VARIANT 7 7 E -> G (in dbSNP:rs11031357) /FTId=VAR_037284 VARIANT 83 83 V -> M (in dbSNP:rs2761591) /FTId=VAR_033767 CONFLICT 192 192 V -> A (in Ref. 1; AAP75563) SEQUENCE 354 AA; 39859 MW; 4C30ED8D93F7FBEE CRC64; MAKTGAEDHR EALSQSSLSL LTEAMEVLQQ SSPEGTLDGN TVNPIYKYIL NDLPREFMSS QAKAVIKTTD DYLQSQFGPN RLVHSAAVSE GSGLQDCSTH QTASDHSHDE ISDLDSYKSN SKNNSCSISA SKRNRPVSAP VGQLRVAEFS SLKFQSARNW QKLSQRHKLQ PRVIKVTAYK NGSRTVFARV TVPTITLLLE ECTEKLNLNM AARRVFLADG KEALEPEDIP HEADVYVSTG EPFLNPFKKI KDHLLLIKKV TWTMNGLMLP TDIKRRKTKP VLSIRMKKLT ERTSVRILFF KNGMGQDGHE ITVGKETMKK VLDTCTIRMN LNLPARYFYD LYGRKIEDIS KGKH
Research Areas
Citations (0)

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Background

This gene encodes a member of the doublecortin family. Theprotein encoded by this gene is a hydrophilic, intracellularprotein. It contains a single doublecortin domain and is unable tobind microtubules and to regulate microtubule polymerization. Thisgene is mainly expressed in adult testis. It does not have a mousehomolog.

References

Dijkmans, T.F., et al. Cent Nerv Syst Agents Med Chem 10(1):32-46(2010)Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009)Reiner, O., et al. BMC Genomics 7, 188 (2006) :Zeng, L., et al. J. Hum. Genet. 48(7):393-396(2003)

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$ 80.00
Cat# BP12315b
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