|Other Names||Hepatocyte growth factor-like protein, Macrophage stimulatory protein, Macrophage-stimulating protein, MSP, Hepatocyte growth factor-like protein alpha chain, Hepatocyte growth factor-like protein beta chain, MST1, D3F15S2, DNF15S2, HGFL|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||D3F15S2, DNF15S2, HGFL|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene contains four kringledomains and a serine protease domain, similar to that found inhepatic growth factor. Despite the presence of the serine proteasedomain, the encoded protein may not have any proteolytic activity.The receptor for this protein is RON tyrosine kinase, which uponactivation stimulates ciliary motility of ciliated epithelial lungcells. This protein is secreted and cleaved to form an alpha chainand a beta chain bridged by disulfide bonds.
Latiano, A., et al. Inflamm. Bowel Dis. 16(7):1108-1117(2010)Morgan, A.R., et al. Hum. Immunol. 71(6):602-609(2010)Qiao, M., et al. Mol. Cell 38(4):512-523(2010)McGovern, D.P., et al. Nat. Genet. 42(4):332-337(2010)Oh, H.J., et al. Curr. Biol. 20(5):416-422(2010)
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