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WDR34 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q96EX3
Clone Names 100107066
Peptide ID 100107066
Additional Information
Gene ID 89891
Other Names WD repeat-containing protein 34, WDR34
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDR34
Function Critical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-based intraflagellar transport (IFT) machinery. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Note=Concentrates around the centrioles and basal bodies also showing axonemal staining
Tissue Location Expressed in several cell lines (at protein level).
Research Areas
Citations (0)

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This gene encodes a member of the WD repeat proteinfamily. WD repeats are minimally conserved regions of approximately40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),which may facilitate formation of heterotrimeric or multiproteincomplexes. Members of this family are involved in a variety ofcellular processes, including cell cycle progression, signaltransduction, apoptosis, and gene regulation.


Gao, D., et al. Cell. Mol. Life Sci. 66(15):2573-2584(2009)Humphray, S.J., et al. Nature 429(6990):369-374(2004)

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$ 80.00
Cat# BP12421c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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