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TLX1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P31314
Clone Names 100318018
Peptide ID 100318018
Additional Information
Gene ID 3195
Other Names T-cell leukemia homeobox protein 1, Homeobox protein Hox-11, Proto-oncogene TCL-3, T-cell leukemia/lymphoma protein 3, TLX1, HOX11, TCL3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TLX1
Synonyms HOX11, TCL3
Function Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.
Cellular Location Nucleus.
Research Areas
Citations (0)

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This gene encodes a nuclear transcription factor thatbelongs to the NK-linked or NK-like (NKL) subfamily of homeoboxgenes. The encoded protein is required for normal development ofthe spleen during embryogenesis. This protein is also involved inspecification of neuronal cell fates. Ectopic expression of thisgene due to chromosomal translocations is associated with certainT-cell acute lymphoblastic leukemias. Alternate splicing results inmultiple transcript variants.


De Keersmaecker, K., et al. Nat. Med. 16(11):1321-1327(2010)Milech, N., et al. Leuk. Res. 34(3):358-363(2010)Zweier-Renn, L.A., et al. Genes Chromosomes Cancer 49(2):119-131(2010)Riz, I., et al. Mol. Cancer 9, 181 (2010) :Dear, T.N., et al. Proc. Natl. Acad. Sci. U.S.A. 90(10):4431-4435(1993)

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$ 80.00
Cat# BP12489c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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