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GBP1 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P32455
Clone Names 100318065
Peptide ID 100318065
Additional Information
Gene ID 2633
Other Names Interferon-induced guanylate-binding protein 1, GTP-binding protein 1, GBP-1, HuGBP-1, Guanine nucleotide-binding protein 1, GBP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GBP1
Function Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
Cellular Location Cytoplasm. Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization requires isoprenylation and the presence of another IFN-gamma-induced factor
Research Areas
Citations (0)

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Guanylate binding protein expression is induced byinterferon. Guanylate binding proteins are characterized by theirability to specifically bind guanine nucleotides (GMP, GDP, andGTP) and are distinguished from the GTP-binding proteins by thepresence of 2 binding motifs rather than 3.


Vopel, T., et al. J. Mol. Biol. 400(1):63-70(2010)Mirpuri, J., et al. J. Immunol. 184(12):7186-7195(2010)Lipnik, K., et al. Mol. Med. 16 (5-6), 177-187 (2010) :Davila, S., et al. Genes Immun. 11(3):232-238(2010)O'Doherty, C., et al. Pharmacogenomics 10(7):1177-1186(2009)

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$ 80.00
Cat# BP12492a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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