|Other Names||Profilin-4, Profilin IV, PFN4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Does not bind to actin (PubMed:19419568), contrary to other family members.|
|Cellular Location||Cytoplasm, cytoskeleton.|
|Tissue Location||Detected in testis (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
PFN4 binds to actin and affects the structure of the cytoskeleton (By similarity).
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)Behnen, M., et al. BMC Cell Biol. 10, 34 (2009) :
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