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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PSMB10 Antibody (C-term) Blocking peptide   

PSMB10 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P40306
Clone Names 100311201
Peptide ID 100311201
Additional Information
Gene ID 5699
Other Names Proteasome subunit beta type-10, Low molecular mass protein 10, Macropain subunit MECl-1, Multicatalytic endopeptidase complex subunit MECl-1, Proteasome MECl-1, Proteasome subunit beta-2i, PSMB10, LMP10, MECL1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSMB10
Synonyms LMP10, MECL1
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.
Cellular Location Cytoplasm {ECO:0000255|PROSITE- ProRule:PRU00809}. Nucleus
Research Areas
Citations (0)

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The proteasome is a multicatalytic proteinase complex witha highly ordered ring-shaped 20S core structure. The core structureis composed of 4 rings of 28 non-identical subunits; 2 rings arecomposed of 7 alpha subunits and 2 rings are composed of 7 betasubunits. Proteasomes are distributed throughout eukaryotic cellsat a high concentration and cleave peptides in anATP/ubiquitin-dependent process in a non-lysosomal pathway. Anessential function of a modified proteasome, the immunoproteasome,is the processing of class I MHC peptides. This gene encodes amember of the proteasome B-type family, also known as the T1Bfamily, that is a 20S core beta subunit. Proteolytic processing isrequired to generate a mature subunit. Expression of this gene isinduced by gamma interferon, and this gene product replacescatalytic subunit 2 (proteasome beta 7 subunit) in theimmunoproteasome.


Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Moschonas, A., et al. Mol. Cell. Biol. 28(20):6208-6222(2008)Liu, Y., et al. DNA Seq. 18(4):257-264(2007)Listovsky, T., et al. EMBO J. 23(7):1619-1626(2004)

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$ 80.00
Cat# BP12569b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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