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SENP8 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96LD8
Clone Names 2100404
Peptide ID 2100404
Additional Information
Gene ID 123228
Other Names Sentrin-specific protease 8, Deneddylase-1, NEDD8-specific protease 1, Protease, cysteine 2, Sentrin/SUMO-specific protease SENP8, SENP8, DEN1, NEDP1, PRSC2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1260a was selected from the C-term region of human SENP8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SENP8
Synonyms DEN1, NEDP1, PRSC2
Function Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
Tissue Location Broadly expressed, with highest levels in kidney and pancreas.
Research Areas
Citations (0)

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NEDD8 is a ubiquitin-like protein that becomes conjugated to the cullin subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. SENP8 is a protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.


Wu, K., et al., J. Biol. Chem. 278(31):28882-28891 (2003).Gan-Erdene, T., et al., J. Biol. Chem. 278(31):28892-28900 (2003).Mendoza, H.M., et al., J. Biol. Chem. 278(28):25637-25643 (2003).

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$ 80.00
Cat# BP1260a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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