|Other Names||Squalene monooxygenase, Squalene epoxidase, SE, SQLE, ERG1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway.|
|Cellular Location||Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Squalene epoxidase catalyzes the first oxygenation step insterol biosynthesis and is thought to be one of the rate-limitingenzymes in this pathway.
Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)Helms, M.W., et al. Br. J. Cancer 99(5):774-780(2008)Liu, Y., et al. Lung Cancer 56(3):307-317(2007)
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