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MED22 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q15528
Clone Names 100324134
Peptide ID 100324134
Additional Information
Gene ID 6837
Other Names Mediator of RNA polymerase II transcription subunit 22, Mediator complex subunit 22, Surfeit locus protein 5, Surf-5, MED22, SURF5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MED22
Synonyms SURF5
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Cellular Location Nucleus.
Research Areas
Citations (0)

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This gene is located in the surfeit gene cluster, a groupof very tightly linked housekeeping genes that do not sharesequence similarity. The gene is oriented in a head-to-head fashionwith RPL7A (SURF3) and the two genes share a bidirectionalpromoter. The encoded proteins are localized to the cytoplasm. Twoalternative transcript variants encoding different isoforms havebeen identified for this gene.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Sato, S., et al. Mol. Cell 14(5):685-691(2004)Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) :

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$ 80.00
Cat# BP12666a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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