|Other Names||GTP-binding protein 10, Protein obg homolog 2, ObgH2, GTPBP10, OBGH2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nuceleolar architecture is observed.|
|Cellular Location||Nucleus, nucleolus. Chromosome. Note=Found in the dense fibrillar compartment region of the nucleolus. At the onset of mitosis moves to the chromosome surface and remains there until anaphase Gradually re-assembles into the nucleolus at late anaphase to telophase|
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Provided below are standard protocols that you may find useful for product applications.
Small G proteins, such as GTPBP10, act as molecularswitches that play crucial roles in the regulation of fundamentalcellular processes such as protein synthesis, nuclear transport,membrane trafficking, and signal transduction (Hirano et al., 2006[PubMed 17054726]).
Hirano, Y., et al. Genes Cells 11(11):1295-1304(2006)
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