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FGFRL1 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8N441
Clone Names 100324095
Peptide ID 100324095
Additional Information
Gene ID 53834
Other Names Fibroblast growth factor receptor-like 1, FGF receptor-like protein 1, FGF homologous factor receptor, FGFR-like protein, Fibroblast growth factor receptor 5, FGFR-5, FGFRL1, FGFR5, FHFR
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms FGFR5, FHFR
Function Has a negative effect on cell proliferation.
Cellular Location Membrane; Single-pass type I membrane protein Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles
Tissue Location Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of thefibroblast growth factor receptor (FGFR) family, where amino acidsequence is highly conserved between members and throughoutevolution. FGFR family members differ from one another in theirligand affinities and tissue distribution. A full-lengthrepresentative protein would consist of an extracellular region,composed of three immunoglobulin-like domains, a single hydrophobicmembrane-spanning segment and a cytoplasmic tyrosine kinase domain.The extracellular portion of the protein interacts with fibroblastgrowth factors, setting in motion a cascade of downstream signals,ultimately influencing mitogenesis and differentiation. A markeddifference between this gene product and the other family membersis its lack of a cytoplasmic tyrosine kinase domain. The result isa transmembrane receptor that could interact with other familymembers and potentially inhibit signaling. Multiple alternativelyspliced transcript variants encoding the same isoform have beenfound for this gene.


Bailey, S.D., et al. Diabetes Care (2010) In press :Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)LopezJimenez, N., et al. Hum. Genet. 127(3):325-336(2010)Steinberg, F., et al. J. Biol. Chem. 285(3):2193-2202(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 80.00
Cat# BP12726a
Availability: In Stock
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