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SGPL1 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O95470
Clone Names 100324137
Peptide ID 100324137
Additional Information
Gene ID 8879
Other Names Sphingosine-1-phosphate lyase 1, S1PL, SP-lyase 1, SPL 1, hSPL, Sphingosine-1-phosphate aldolase, SGPL1, KIAA1252
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SGPL1 (HGNC:10817)
Function Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.
Cellular Location Endoplasmic reticulum membrane; Single-pass type III membrane protein
Tissue Location Found in liver and kidney.
Research Areas
Citations (0)

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Background

SGPL1 cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.

References

Seo, Y.J., et al. J. Virol. 84(16):8124-8131(2010)Vogel, P., et al. PLoS ONE 4 (1), E4112 (2009) :Peest, U., et al. J. Cell. Biochem. 104(3):756-772(2008)Morgan, A.R., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B (6), 762-770 (2007) :Oskouian, B., et al. Proc. Natl. Acad. Sci. U.S.A. 103(46):17384-17389(2006)

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$ 80.00
Cat# BP12736a
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