|Other Names||Zinc transporter 7, ZnT-7, Solute carrier family 30 member 7, Znt-like transporter 2, SLC30A7, ZNT7, ZNTL2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity).|
|Cellular Location||Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Zinc functions as a cofactor for numerous enzymes, nuclearfactors, and hormones and as an intra- and intercellular signalion. Members of the zinc transporter (ZNT)/SLC30 subfamily of thecation diffusion facilitator family, such as SLC30A7, permitcellular efflux of zinc (Seve et al., 2004 [PubMed15154973]).
Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)Zhang, L.H., et al. Brain Res. Bull. 77(1):55-60(2008)Overbeck, S., et al. J. Leukoc. Biol. 83(2):368-380(2008)Falcon-Perez, J.M., et al. Exp. Cell Res. 313(7):1473-1483(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
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