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SLC30A7 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8NEW0 |
|---|---|
| Clone Names | 100324140 |
| Gene ID | 148867 |
|---|---|
| Other Names | Zinc transporter 7, ZnT-7, Solute carrier family 30 member 7, Znt-like transporter 2, SLC30A7, ZNT7, ZNTL2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC30A7 (HGNC:19306) |
|---|---|
| Function | Zinc ion transporter mediating zinc entry from the cytosol into the lumen of organelles along the secretory pathway (PubMed:15525635, PubMed:15994300). By contributing to zinc ion homeostasis within the early secretory pathway, regulates the activation and folding of enzymes like alkaline phosphatases (PubMed:15525635, PubMed:15994300). |
| Cellular Location | Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q9JKN1} Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q9JKN1} Sarcoplasmic reticulum {ECO:0000250|UniProtKB:Q5BJM8}. Mitochondrion {ECO:0000250|UniProtKB:Q5BJM8} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Zinc functions as a cofactor for numerous enzymes, nuclearfactors, and hormones and as an intra- and intercellular signalion. Members of the zinc transporter (ZNT)/SLC30 subfamily of thecation diffusion facilitator family, such as SLC30A7, permitcellular efflux of zinc (Seve et al., 2004 [PubMed15154973]).
References
Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)Zhang, L.H., et al. Brain Res. Bull. 77(1):55-60(2008)Overbeck, S., et al. J. Leukoc. Biol. 83(2):368-380(2008)Falcon-Perez, J.M., et al. Exp. Cell Res. 313(7):1473-1483(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
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