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SIX5 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8N196
Clone Names 100324152
Peptide ID 100324152
Additional Information
Gene ID 147912
Other Names Homeobox protein SIX5, DM locus-associated homeodomain protein, Sine oculis homeobox homolog 5, SIX5, DMAHP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SIX5
Synonyms DMAHP
Function Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'- TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity).
Cellular Location Cytoplasm. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12500905}
Tissue Location Expressed in adult but not in fetal eyes. Found in corneal epithelium and endothelium, lens epithelium, ciliary body epithelia, cellular layers of the retina and the sclera.
Research Areas
Citations (0)

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The protein encoded by this gene is ahomeodomain-containing transcription factor that appears tofunction in the regulation of organogenesis. This gene is locateddownstream of the dystrophia myotonica-protein kinase gene.Mutations in this gene are a cause of branchiootorenal syndrometype 2.


Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)Hoskins, B.E., et al. Am. J. Hum. Genet. 80(4):800-804(2007)Sato, S., et al. Hum. Mol. Genet. 11(9):1045-1058(2002)Fougerousse, F., et al. J. Muscle Res. Cell. Motil. 23(3):255-264(2002)

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$ 80.00
Cat# BP12740c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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