|Other Names||Dystrophin-related protein 2, DRP-2, DRP2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Possibly involved in membrane-cytoskeleton interactions of the central nervous system.|
|Cellular Location||Cytoplasm, cytoskeleton|
|Tissue Location||Brain and spinal cord; very low levels in eye, ovary, epididymis and testis; not in cardiac and skeletal muscle|
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Members of the dystrophin family of proteins perform acritical role in the maintenance of membrane-associated complexesat points of intercellular contact in vertebrate cells. The proteinencoded by this gene is predicted to resemble certain shortC-terminal isoforms of dystrophin and dystrophin-related protein 1(DRP1 or utrophin). DRP2 is expressed principally in the brain andspinal cord. Two transcript variants encoding different isoformshave been found for this gene.
Pasalic, D., et al. Mol. Biol. Rep. 36(4):775-780(2009)Sediva, A., et al. J. Clin. Immunol. 27(6):640-646(2007)van Oijen, M., et al. Neurobiol. Aging 28(9):1361-1366(2007)Suk Danik, J., et al. Ann. Hum. Genet. 70 (PT 6), 705-716 (2006) :Ujike, H., et al. Ann. N. Y. Acad. Sci. 1074, 90-96 (2006) :
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