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TTF-1 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q15361
Clone Names 80722105
Peptide ID 80722105
Additional Information
Gene ID 7270
Other Names Transcription termination factor 1, TTF-1, RNA polymerase I termination factor, Transcription termination factor I, TTF-I, TTF1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TTF1
Function Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.
Cellular Location Nucleus. Nucleus, nucleolus.
Research Areas
Citations (0)

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Background

The TTF1 gene encodes a transcription termination factorthat regulates ribosomal gene transcription (summarized by Green etal., 2010 [PubMed 20448178]).

References

Montanelli, L., et al. Mol. Cell. Endocrinol. 322 (1-2), 64-71 (2010) :Lessard, F., et al. Mol. Cell 38(4):539-550(2010)Green, R.E., et al. Science 328(5979):710-722(2010)McCluggage, W.G., et al. Am. J. Surg. Pathol. 34(4):525-532(2010)Kreil, S., et al. Leuk. Res. 33 (9), E168-E169 (2009) :

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$ 80.00
Cat# BP12764a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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