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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   SPAG8 Antibody (C-term) Blocking peptide   

SPAG8 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q99932
Clone Names 100405075
Peptide ID 100405075
Additional Information
Gene ID 26206
Other Names Sperm-associated antigen 8, HSD-1, Sperm membrane protein 1, SMP-1, Sperm membrane protein BS-84, SPAG8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPAG8
Function May play a role in fertility and microtubule formation through interaction with RANBP9.
Cellular Location Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Acrosomal region of the head of mature sperm cells
Tissue Location Expressed in testis (germ cells), but not in liver, kidney, prostate and small intestine
Research Areas
Citations (0)

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The correlation of anti-sperm antibodies with cases ofunexplained infertility implicates a role for these antibodies inblocking fertilization. Improved diagnosis and treatment ofimmunologic infertility, as well as identification of proteins fortargeted contraception, are dependent on the identification andcharacterization of relevant sperm antigens. The protein encoded bythis gene is recognized by sperm agglutinating antibodies from aninfertile woman. This protein is localized in germ cells of thetestis at all stages of spermatogenesis and is localized to theacrosomal region of mature spermatozoa. Alternatively splicedvariants that encode different protein isoforms have been describedbut the full-length sequences of only two have been determined.


Wu, H., et al. FEBS Lett. 584(13):2807-2815(2010)Li, R., et al. Cell Biochem. Funct. 27(5):264-268(2009)Cheng, G.Y., et al. Asian J. Androl. 9(1):23-29(2007)Tang, X., et al. J. Mol. Med. 82(6):383-388(2004)Humphray, S.J., et al. Nature 429(6990):369-374(2004)

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$ 80.00
Cat# BP12827b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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