|Other Names||GMP reductase 1, Guanosine 5'-monophosphate oxidoreductase 1, Guanosine monophosphate reductase 1, GMPR, GMPR1|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an enzyme that catalyzes theirreversible and NADPH-dependent reductive deamination of GMP toIMP. The protein also functions in the re-utilization of freeintracellular bases and purine nucleosides.
Chasman, D.I., et al. PLoS Genet. 5 (11), E1000730 (2009) :Lamesch, P., et al. Genomics 89(3):307-315(2007)Mungall, A.J., et al. Nature 425(6960):805-811(2003)Deng, Y., et al. Int. J. Biochem. Cell Biol. 34(9):1035-1050(2002)Salvatore, D., et al. J. Biol. Chem. 273(47):31092-31096(1998)
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