|Other Names||C-terminal-binding protein 2, CtBP2, CTBP2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity).|
|Cellular Location||Nucleus. Cell junction, synapse|
|Tissue Location||Ubiquitous. Highest levels in heart, skeletal muscle, and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
This gene produces alternative transcripts encoding twodistinct proteins. One protein is a transcriptional repressor,while the other isoform is a major component of specializedsynapses known as synaptic ribbons. Both proteins contain a NAD+binding domain similar to NAD+-dependent 2-hydroxyaciddehydrogenases. A portion of the 3' untranslated region was used tomap this gene to chromosome 21q21.3; however, it was noted thatsimilar loci elsewhere in the genome are likely. Blast analysisshows that this gene is present on chromosome 10. [provided byRefSeq].
Bao, B.Y., et al. Clin. Chim. Acta 411 (17-18), 1232-1237 (2010) :Liu, H., et al. Prostate (2010) In press :Kim, S.T., et al. Prostate (2010) In press :Gallagher, D.J., et al. Clin. Cancer Res. 16(10):2819-2832(2010)Kitamura, F., et al. Int. Arch. Allergy Immunol. 152 SUPPL 1, 18-21 (2010) :
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