|Other Names||Protein DGCR6L, DiGeorge syndrome critical region 6-like protein, DGCR6L|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in neural crest cell migration into the third and fourth pharyngeal pouches.|
|Cellular Location||Nucleus. Note=Predominantly nuclear|
|Tissue Location||Widely expressed in fetal and adult tissues. Highest expression in liver, heart and skeletal muscle. Lower levels in pancreas and placenta. Weak expression in brain|
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Provided below are standard protocols that you may find useful for product applications.
This gene, the result of a duplication at this locus, isone of two functional genes encoding nearly identical proteins thathave similar expression patterns. The product of this gene is aprotein that shares homology with the Drosophila gonadal protein,expressed in gonadal tissues and germ cells, and with the humanlaminin gamma-1 chain that functions in cell attachment andmigration. This gene is located in a region of chromosome 22implicated in the DiGeorge syndrome, one facet of a broadercollection of anomalies referred to as the CATCH 22 syndrome.
Li, X., et al. Int. J. Biochem. Cell Biol. 42(1):70-79(2010)Pfuhl, T., et al. Hum. Genet. 117(1):70-80(2005)Edelmann, L., et al. Genome Res. 11(2):208-217(2001)
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