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SIM1 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P81133
Clone Names 100324039
Peptide ID 100324039
Additional Information
Gene ID 6492
Other Names Single-minded homolog 1, Class E basic helix-loop-helix protein 14, bHLHe14, SIM1, BHLHE14
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SIM1
Synonyms BHLHE14
Function Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00632, ECO:0000255|PROSITE-ProRule:PRU00981}
Research Areas
Citations (0)

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SIM1 and SIM2 genes are Drosophila single-minded (sim)gene homologs. SIM1 transcript was detected only in fetal kidneyout of various adult and fetal tissues tested. Since the sim geneplays an important role in Drosophila development and has peaklevels of expression during the period of neurogenesis,it wasproposed that the human SIM gene is a candidate for involvement incertain dysmorphic features (particularly the facial and skullcharacteristics), abnormalities of brain development, and/or mentalretardation of Down syndrome.


Ghoussaini, M., et al. Obesity (Silver Spring) 18(8):1670-1675(2010)Tolson, K.P., et al. J. Neurosci. 30(10):3803-3812(2010)Traurig, M., et al. Diabetes 58(7):1682-1689(2009)Gregorio, S.P., et al. Psychiatry Res 165 (1-2), 1-9 (2009) :Hung, C.C., et al. Int J Obes (Lond) 31(3):429-434(2007)

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$ 80.00
Cat# BP12960a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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