FPR3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P25089 |
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Clone Names | 100324210 |
Gene ID | 2359 |
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Other Names | N-formyl peptide receptor 3, FMLP-related receptor II, FMLP-R-II, Formyl peptide receptor-like 2, FPR3, FPRH1, FPRL2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | FPR3 |
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Synonyms | FPRH1, FPRL2 |
Function | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Acts as a receptor for humanin (PubMed:15465011). |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Detected in various tissues with highest expression in lung. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Kim, S.D., et al. J. Immunol. 183(9):5511-5517(2009)Devosse, T., et al. J. Immunol. 182(8):4974-4984(2009)Lambert, N.A. Sci Signal 1 (25), RE5 (2008) :Lee, H.Y., et al. Biochem. Biophys. Res. Commun. 359(4):985-990(2007)
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