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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   HPSE2 Antibody (C-term) Blocking peptide   

HPSE2 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8WWQ2
Other Accession NP_001159716.1, NP_068600.4, NP_001159717.1, NP_001159718.1
Clone Names 100405171
Peptide ID 100405171
Additional Information
Gene ID 60495
Other Names Inactive heparanase-2, Hpa2, HPSE2, HPA2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HPSE2
Synonyms HPA2
Function Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro).
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Widely expressed, with the highest expression in brain, mammary gland, prostate, small intestine, testis and uterus. In the central nervous system, expressed in the spinal chord, caudate nucleus, thalamus, substantia nigra, medulla oblongata, putamen and pons. In the urinary bladder, expressed in longitudinal and circular layers of detrusor muscle. Found both in normal and cancer tissues.
Research Areas
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Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.

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$ 80.00
Cat# BP12994c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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