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ARHGAP22 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q7Z5H3
Clone Names 91216030
Peptide ID 91216030
Additional Information
Gene ID 58504
Other Names Rho GTPase-activating protein 22, Rho-type GTPase-activating protein 22, ARHGAP22, RHOGAP2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RHOGAP2
Function Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity).
Cellular Location Cytoplasm. Nucleus. Note=Mainly cytoplasmic. Some fraction is nuclear (By similarity).
Research Areas
Citations (0)

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ARHGAPs, such as ARHGAP22, encode negative regulators ofRho GTPases (see ARHA; MIM 165390), which are implicated in actinremodeling, cell polarity, and cell migration (Katoh and Katoh,2004 [PubMed 15254788]).


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Dick, D.M., et al. Mol. Psychiatry (2010) In press :Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)Katoh, M., et al. Int. J. Mol. Med. 14(2):333-338(2004)

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$ 80.00
Cat# BP13013b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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