|Other Names||Torsin-1B, Torsin ATPase-1B, 364-, Torsin family 1 member B, TOR1B, DQ1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. Plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity. May have a redundant function with TOR1A in non-neural tissues.|
|Cellular Location||Endoplasmic reticulum lumen. Nucleus membrane|
|Tissue Location||Widely expressed with low levels in brain.|
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TOR1B may serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins (By similarity).
Sharma, N., et al. Mov. Disord. (2010) In press :Kamm, C., et al. Neurology 67(10):1857-1859(2006)Bahn, E., et al. Brain Res. 1116(1):112-119(2006)Hewett, J.W., et al. J. Neurochem. 89(5):1186-1194(2004)Humphray, S.J., et al. Nature 429(6990):369-374(2004)
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