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NIT1 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q86X76
Clone Names 100406174
Peptide ID 100406174
Additional Information
Gene ID 4817
Other Names Nitrilase homolog 1, 35--, NIT1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NIT1
Function Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2 (By similarity).
Cellular Location Cytoplasm. Mitochondrion.
Tissue Location Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas
Research Areas
Citations (0)

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This gene encodes a member of the nitrilase protein familywith homology to bacterial and plant nitrilases, enzymes thatcleave nitriles and organic amides to the corresponding carboxylicacids plus ammonia. Multiple transcript variants encoding differentisoforms have been found for this gene.


Semba, S., et al. J. Biol. Chem. 281(38):28244-28253(2006)Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)Pekarsky, Y., et al. Proc. Natl. Acad. Sci. U.S.A. 95(15):8744-8749(1998)

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$ 80.00
Cat# BP13042b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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