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PGR/PR Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P06401
Clone Names 101229023
Peptide ID 101229023
Additional Information
Gene ID 5241
Other Names Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PGR
Synonyms NR3C3
Function The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.
Cellular Location Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both homone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases Isoform 4: Mitochondrion outer membrane
Research Areas
Citations (0)

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This gene encodes a member of the steroid receptorsuperfamily. The encoded protein mediates the physiological effectsof progesterone, which plays a central role in reproductive eventsassociated with the establishment and maintenance of pregnancy.This gene uses two distinct promotors and translation start sitesin the first exon to produce two isoforms, A and B. The twoisoforms are identical except for the additional 165 amino acidsfound in the N-terminus of isoform B and mediate their own responsegenes and physiologic effects with little overlap. The location oftranscription initiation for isoform A has not been clearlydetermined.


Geradts, J., et al. Cancer Invest. 28(9):969-977(2010)Tang, P., et al. Cancer Invest. 28(9):978-982(2010)Van Belle, V., et al. J. Clin. Oncol. 28(27):4129-4134(2010)Taylor, K.C., et al. Horm Res Paediatr (2010) In press :Near, A.M., et al. Fertil. Steril. (2010) In press :

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$ 80.00
Cat# BP13057c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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