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ATAD2 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q6PL18
Clone Names 110111072
Peptide ID 110111072
Additional Information
Gene ID 29028
Other Names ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated protein, ANCCA, ATAD2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATAD2
Function May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
Cellular Location Nucleus.
Tissue Location Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors
Research Areas
Citations (0)

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A large family of ATPases has been described, whose keyfeature is that they share a conserved region of about 220 aminoacids that contains an ATP-binding site. The proteins that belongto this family either contain one or two AAA (ATPases Associatedwith diverse cellular Activities) domains. AAA family proteinsoften perform chaperone-like functions that assist in the assembly,operation, or disassembly of protein complexes. The protein encodedby this gene contains two AAA domains, as well as a bromodomain.


Revenko, A.S., et al. Mol. Cell. Biol. 30(22):5260-5272(2010)Ciro, M., et al. Cancer Res. 69(21):8491-8498(2009)Zou, J.X., et al. Cancer Res. 69(8):3339-3346(2009)Zou, J.X., et al. Proc. Natl. Acad. Sci. U.S.A. 104(46):18067-18072(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 80.00
Cat# BP13073a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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