|Other Names||Nuclear speckle splicing regulatory protein 1, Coiled-coil domain-containing protein 55, Nuclear speckle-related protein 70, NSrp70, NSRP1, CCDC55, NSRP70|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||RNA-binding protein that mediates pre-mRNA alternative splicing regulation.|
|Cellular Location||Nucleus. Nucleus speckle. Note=Colocalizes with splicing factors SRSF1 and SRSF2 in speckles|
|Tissue Location||Expressed in dendritic cells, T-cells, B-cells and natural killer cells. Expressed in secondary lymphoid organs such as spleen and mesenteric, axillary and brachial lymph nodes|
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Provided below are standard protocols that you may find useful for product applications.
Horikawa, Y., et al. Clin. Cancer Res. 14(23):7956-7962(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
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