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Hrk BH3 Domain Antibody Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O00198
Other Accession NP_003797
Clone Names 2011201
Additional Information
Gene ID 8739
Other Names Activator of apoptosis harakiri, BH3-interacting domain-containing protein 3, Neuronal death protein DP5, HRK, BID3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1311a was selected from the region of human Hrk BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HRK
Synonyms BID3
Function Promotes apoptosis.
Cellular Location Membrane; Single-pass membrane protein. Mitochondrion
Research Areas
Citations (0)

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Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL.


Wakabayashi, T., et al., Neurosci. Lett. 318(2):77-80 (2002).Inohara, N., et al., EMBO J. 16(7):1686-1694 (1997).

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$ 80.00
Cat# BP1311a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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