|Other Names||Eukaryotic translation initiation factor 1A, Y-chromosomal, eIF-1A Y isoform, Eukaryotic translation initiation factor 4C, eIF-4C, EIF1AY|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13157a was selected from the N-term region of EIF1AY. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein similar to eukaryotictranslation initiation factor 1A (EIF1A). EIF1A is required for thebinding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi andeIF3) to the 5' end of capped RNA.
Serajee, F.J., et al. J. Child Neurol. 24(10):1258-1261(2009)Lim, J., et al. Cell 125(4):801-814(2006)Fortna, A., et al. PLoS Biol. 2 (7), E207 (2004) :Agate, R.J., et al. Mol. Biol. Evol. 21(2):384-396(2004)Skaletsky, H., et al. Nature 423(6942):825-837(2003)
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