CNTLN Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NXG0 |
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Clone Names | 91230161 |
Gene ID | 54875 |
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Other Names | Centlein, Centrosomal protein, CNTLN, C9orf101, C9orf39 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13167a was selected from the N-term region of CNTLN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CNTLN |
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Synonyms | C9orf101, C9orf39 |
Function | Required for centrosome cohesion and recruitment of CEP68 to centrosomes. |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Colocalizes with gamma-tubulin during interphase and mitosis Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase (By similarity). Localizes to the proximal ends of the centrioles (PubMed:24554434). Levels are high at interphase centrosomes but are reduced on mitotic spindle poles (PubMed:24554434). {ECO:0000250|UniProtKB:A9ZSY0, ECO:0000269|PubMed:24554434} |
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Provided below are standard protocols that you may find useful for product applications.
Background
The specific function of this protein remains unknown.
References
Bailey, S.D., et al. Diabetes Care (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Song, H., et al. Nat. Genet. 41(9):996-1000(2009)Makino, K., et al. Biochem. Biophys. Res. Commun. 366(4):958-962(2008)
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