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CNTLN Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NXG0
Clone Names 91230161
Peptide ID 91230161
Additional Information
Gene ID 54875
Other Names Centlein, Centrosomal protein, CNTLN, C9orf101, C9orf39
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13167a was selected from the N-term region of CNTLN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNTLN
Synonyms C9orf101, C9orf39
Function Required for centrosome cohesion and recruitment of CEP68 to centrosomes.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Colocalizes with gamma-tubulin during interphase and mitosis. Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase (By similarity). Localizes to the proximal ends of the centrioles (PubMed:24554434). Levels are high at interphase centrosomes but are reduced on mitotic spindle poles (PubMed:24554434). {ECO:0000250|UniProtKB:A9ZSY0, ECO:0000269|PubMed:24554434}
Research Areas
Citations (0)

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Background

The specific function of this protein remains unknown.

References

Bailey, S.D., et al. Diabetes Care (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Song, H., et al. Nat. Genet. 41(9):996-1000(2009)Makino, K., et al. Biochem. Biophys. Res. Commun. 366(4):958-962(2008)

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$ 80.00
Cat# BP13167a
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