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IGF1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P05019
Clone Names 110111013
Peptide ID 110111013
Additional Information
Gene ID 3479
Other Names Insulin-like growth factor I, IGF-I, Mechano growth factor, MGF, Somatomedin-C, IGF1, IBP1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13212b was selected from the C-term region of IGF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IGF1
Synonyms IBP1
Function The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.
Cellular Location Secreted.
Research Areas
Citations (0)

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The protein encoded by this gene is similar to insulin infunction and structure and is a member of a family of proteinsinvolved in mediating growth and development. The encoded proteinis processed from a precursor, bound by a specific receptor, andsecreted. Defects in this gene are a cause of insulin-like growthfactor I deficiency. Several transcript variants encoding differentisoforms have been found for this gene.


Li, M., et al. J. Biol. Chem. 285(40):30480-30488(2010)Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Szczesny, G., et al. Arch Orthop Trauma Surg (2010) In press :

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$ 80.00
Cat# BP13212b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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