|Other Names||GTPase IMAP family member 8, Immune-associated nucleotide-binding protein 9, IAN-9, Protein IanT, GIMAP8, IAN9, IANT|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13234a was selected from the N-term region of GIMAP8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections.|
|Cellular Location||Endoplasmic reticulum. Golgi apparatus. Mitochondrion. Cytoplasm, cytosol|
|Tissue Location||Detected in T-cells.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein belonging to the GTP-bindingsuperfamily and to the immuno-associated nucleotide (IAN) subfamilyof nucleotide-binding proteins. In humans, the IAN subfamily genesare located in a cluster at 7q36.1.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Davila, S., et al. Genes Immun. 11(3):232-238(2010)Dion, C., et al. Int. Immunol. 17(9):1257-1268(2005)Krucken, J., et al. Gene 341, 291-304 (2004) :Cambot, M., et al. Blood 99(9):3293-3301(2002)
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