|Other Names||Peptidase inhibitor 15, PI-15, 25 kDa trypsin inhibitor, p25TI, Cysteine-rich secretory protein 8, CRISP-8, SugarCrisp, PI15, CRISP8, P25TI|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13330a was selected from the N-term region of PI15. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Serine protease inhibitor which displays weak inhibitory activity against trypsin (PubMed:8882727). May play a role in facial patterning during embryonic development (By similarity).|
|Tissue Location||Weakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a trypsin inhibitor. The protein sharessimilarity to insect venom allergens, mammalian testis-specificproteins and plant pathogenesis-related proteins. It is frequentlyexpressed in human neuroblastoma and glioblastoma cell lines, andthus may play a role in the central nervous system. [provided byRefSeq].
Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008) :Kaplan, F., et al. Am. J. Physiol. 276 (6 PT 1), L1027-L1036 (1999) :Yamakawa, T., et al. Biochim. Biophys. Acta 1395(2):202-208(1998)Yamakawa, T., et al. Biochim. Biophys. Acta 1395(2):202-208(1998)Koshikawa, N., et al. J. Biochem. 119(2):334-339(1996)
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