|Other Names||Trimeric intracellular cation channel type B, TRIC-B, TRICB, Transmembrane protein 38B, TMEM38B, C9orf87|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13336b was selected from the C-term region of TMEM38B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity).
Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010)Perry, J.R., et al. Nat. Genet. 41(6):648-650(2009)Yamazaki, D., et al. Pharmacol. Ther. 121(3):265-272(2009)Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008) :
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