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CCDC120 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96HB5
Clone Names 100422019
Peptide ID 100422019
Additional Information
Gene ID 90060
Other Names Coiled-coil domain-containing protein 120, CCDC120
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13363a was selected from the N-term region of CCDC120. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCDC120
Function Required for neurite growth. Localizes CYTH2 to vesicles to allow its transport along neurites, and subsequent ARF6 activation and neurite growth.
Cellular Location Cytoplasm. Cell projection. Cell projection, growth cone. Endosome. Note=In differentiating neuroblastoma cells, colocalizes with CYTH2 in both neurite shaft and growth cone areas. Partially colocalizes with endosomes along neurites in differentiating neuroblastoma cells
Research Areas
Citations (0)

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Background

This gene encodes a protein that contains a coiled-coildomain. Four alternatively spliced transcript variants that encodedifferent protein isoforms have been described for this gene.

References

Xin, X., et al. Genome Res. 19(7):1262-1269(2009)Tarpey, P.S., et al. Nat. Genet. 41(5):535-543(2009)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)

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$ 80.00
Cat# BP13363a
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