|Other Names||BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3, hBACURD3, BTB/POZ domain-containing protein KCTD10, Potassium channel tetramerization domain-containing protein 10, KCTD10, ULR061|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13390b was selected from the C-term region of KCTD10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity).
Keebler, M.E., et al. Circ Cardiovasc Genet 3(4):358-364(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Junyent, M., et al. Am. J. Clin. Nutr. 90(3):686-694(2009)Wang, Y., et al. J. Cell. Biochem. 106(3):409-413(2009)Liu, R., et al. FEBS J. 276(4):1114-1124(2009)
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