|Other Names||Tomoregulin-1, TR-1, H7365, Transmembrane protein with EGF-like and one follistatin-like domain, TMEFF1, C9orf2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13412b was selected from the C-term region of TMEFF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
TMEFF1 may inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.
Letra, A., et al. Am. J. Med. Genet. A 152A (7), 1701-1710 (2010) :Harms, P.W., et al. Genes Dev. 17(21):2624-2629(2003)Gery, S., et al. Oncogene 22(18):2723-2727(2003)Eib, D.W., et al. Cytogenet. Cell Genet. 81 (3-4), 180-181 (1998) :Eib, D.W., et al. J. Neurochem. 67(3):1047-1055(1996)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.