CCDC51 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96ER9 |
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Clone Names | 100422003 |
Gene ID | 79714 |
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Other Names | Coiled-coil domain-containing protein 51, CCDC51 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13421b was selected from the C-term region of CCDC51. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CCDC51 (HGNC:25714) |
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Function | Mitochondrial potassium channel located in the mitochondrial inner membrane (PubMed:31435016). Together with ABCB8/MITOSUR, forms a protein complex localized in the mitochondria that mediates ATP- dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (PubMed:31435016). May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume (PubMed:31435016). |
Cellular Location | Mitochondrion inner membrane; Multi-pass membrane protein |
Tissue Location | Isoform 1: Widely expressed (PubMed:31435016). Isoform 2: Expression is barely detectable (PubMed:31435016) |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
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