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GNG10 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P50151 |
|---|---|
| Clone Names | 91013035 |
| Gene ID | 2790 |
|---|---|
| Other Names | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10, GNG10, GNGT10 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13439a was selected from the N-term region of GNG10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GNG10 |
|---|---|
| Synonyms | GNGT10 |
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Interacts with beta-1 and beta-2, but not with beta-3. |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side |
| Tissue Location | Abundantly and ubiquitously expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Interacts with beta-1 and beta-2, but not with beta-3.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)Jiang, G., et al. Am. J. Physiol. Endocrinol. Metab. 284 (4), E671-E678 (2003) :Ray, K., et al. J. Biol. Chem. 270(37):21765-21771(1995)
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