|Other Names||Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10, GNG10, GNGT10|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13439a was selected from the N-term region of GNG10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
|Tissue Location||Abundantly and ubiquitously expressed.|
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Provided below are standard protocols that you may find useful for product applications.
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Interacts with beta-1 and beta-2, but not with beta-3.
Lamesch, P., et al. Genomics 89(3):307-315(2007)Jiang, G., et al. Am. J. Physiol. Endocrinol. Metab. 284 (4), E671-E678 (2003) :Ray, K., et al. J. Biol. Chem. 270(37):21765-21771(1995)
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