|Other Names||Ras-related protein Rab-5C, L1880, RAB5L, RAB5C, RABL|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13450b was selected from the C-term region of RAB5C. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Protein transport. Probably involved in vesicular traffic (By similarity).|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV|
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Provided below are standard protocols that you may find useful for product applications.
Members of the Rab protein family are small GTPases of theRas superfamily that are thought to ensure fidelity in the processof docking and/or fusion of vesicles with their correct acceptorcompartment (Han et al., 1996 [PubMed 8646882]).
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Chi, A., et al. J. Proteome Res. 5(11):3135-3144(2006)Merithew, E., et al. J. Biol. Chem. 278(10):8494-8500(2003)Clemens, D.L., et al. Infect. Immun. 68(5):2671-2684(2000)Bucci, C., et al. Biochem. Biophys. Res. Commun. 258(3):657-662(1999)
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