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TUBA4A Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P68366
Clone Names 100427025
Peptide ID 100427025
Additional Information
Gene ID 7277
Other Names Tubulin alpha-4A chain, Alpha-tubulin 1, Testis-specific alpha-tubulin, Tubulin H2-alpha, Tubulin alpha-1 chain, TUBA4A, TUBA1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13535b was selected from the C-term region of TUBA4A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TUBA4A
Synonyms TUBA1
Function Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Cellular Location Cytoplasm, cytoskeleton.
Research Areas
Citations (0)

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Background

Microtubules of the eukaryotic cytoskeleton performessential and diverse functions and are composed of a heterodimerof alpha and beta tubulin. The genes encoding these microtubuleconstituents are part of the tubulin superfamily, which is composedof six distinct families. Genes from the alpha, beta and gammatubulin families are found in all eukaryotes. The alpha and betatubulins represent the major components of microtubules, whilegamma tubulin plays a critical role in the nucleation ofmicrotubule assembly. There are multiple alpha and beta tubulingenes and they are highly conserved among and between species. Thisgene encodes an alpha tubulin that is a highly conserved homolog ofa rat testis-specific alpha tubulin.

References

Houck, S.A., et al. PLoS ONE 5 (7), E11795 (2010) :Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)Petretti, C., et al. EMBO Rep. 7(4):418-424(2006)Fiore, G., et al. Neurosci. Lett. 394(1):57-62(2006)

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$ 80.00
Cat# BP13535b
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