|Other Names||Nuclear fragile X mental retardation-interacting protein 2, 82 kDa FMRP-interacting protein, 82-FIP, Cell proliferation-inducing gene 1 protein, FMRP-interacting protein 2, NUFIP2, KIAA1321|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13566c was selected from the Center region of NUFIP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Nucleus. Cytoplasm Note=Distribution is cell cycle-modulated, being cytoplasmic in the G2/M phase and accumulating in nucleus during the G1 phase (PubMed:12837692). Upon cellular stress, relocalizes to stress granules (PubMed:26184334).|
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Provided below are standard protocols that you may find useful for product applications.
NUFIP2 binds RNA.
Soranzo, N., et al. Nat. Genet. 41(11):1182-1190(2009)Meisinger, C., et al. Am. J. Hum. Genet. 84(1):66-71(2009)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Vertegaal, A.C., et al. Mol. Cell Proteomics 5(12):2298-2310(2006)
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